Abstract A Totally Distributed Genetic Algorithm: From a Cellular System to the Mesh of Processors Sekanina, L., Dvoøák, V. The paper deals with properties of the totally distributed genetic algorithm RGA, initially designed for the PIG cellular system. We have adopted the algorithm to a mesh of processors. Simulations were performed using Transim tool in order to investigate performance of this new RGA algorithm independently of a given application. This way, characteristics such as efficiency, speedup, communication delays, the influence of chromosome length and fitness calculations are easily evaluated beforehand.